Oprah joins wave of celebrities who revealed dramatic weight loss in 2025 Celebrities have embraced GLP-1 medications for dramatic weight loss in 2025. Oprah Winfrey, Amy Schumer, Meghan Trainor and Lizzo share their health journeys. Original Source: https://www.foxnews.com/health/oprah-joins-wave-celebrities-who-revealed-dramatic-weight-loss-2025